Download PDF by Keith Green (auth.), Keith Green, Henry F. Edelhauser,: Advances in Ocular Toxicology

By Keith Green (auth.), Keith Green, Henry F. Edelhauser, Robert B. Hackett, David S. Hull, David E. Potter, Ramesh C. Tripathi (eds.)

ISBN-10: 146137720X

ISBN-13: 9781461377207

ISBN-10: 1461559375

ISBN-13: 9781461559375

This quantity represents the complaints of the 5th Congress of the foreign Society of Ocular Toxicology (ISOT), which was once held on the Grove Park lodge and inn in Asheville, North Carolina, October 13-17, 1996. we're extremely joyful to give this quantity to the ophthalmic neighborhood, specially people with an important curiosity in ocular toxicol­ ogy. The 5th Congress used to be built round subject matters when it comes to ocular drug metabolism, the ocular pathophysiological results of nitric oxide, govt matters when it comes to using replacement tools for toxicity checking out, and a workshop that encompassed comparisons of either in vitro as opposed to in vivo versions in addition to diverse animal versions. the result of this congress, embodied during this quantity, is a contribution to the methodologies presently hired or below improvement and to numerous drug or actual results on diverse ocular tissues. whereas the focal point of this complaints is on ocular results of gear or different fabrics, some of the contributions care for themes that experience a much wider curiosity. The workshop about the use of other version structures and the alternative of the simplest animal version for drug trying out covers quite a lot of pursuits that ex­ has a tendency a ways past particular ocular results. this can be very true within the region of other equipment and within the collection of the simplest animal version for exam of alternative illness entities.

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Davis KL, Conners MS, Dunn MW, Schwartzman ML. Induction of corneal epithelial cytochrome P450 arachidonate metabolism by contact lens wear. Invest Ophthalmol Vis Sci 1992;33:291-297. 4. Conners MS, Stoltz RA, Webb SC, Rosenberg J, Dunn MW, Abraham NG, Schwartzman ML. A closed eye contact lens model of corneal inflammation. Part I: Increase synthesis of cytochrome P450 arachidonic acid metabolism. Invest Ophthalmol Vis Sci 1995;36:828--840. 5. Conners MS, Stoltz RA, Davis KL, Dunn MW, Abraham NG, Levere RD, Schwartzman ML.

Laniado Schwartzman M, Stoltz RA, Conners MS, Dunn MW, Mastyugin V, Abraham NG. Cytochrome P450 (CYPIAI) expression and monooxygenase-derived arachidonic acid (AA) metabolism in the rabbit corneal epithelium following injury. Invest Ophthalmol Vis Sci 1996; 37:S356. 76. Nishimura M, Schwartzman ML, Falck JR, Lumin S, Zirrolli JA, Murphy RC. Metabolism of 12(R)-hydroxy-5,8, I 0, 14-eicosatrienoic acid (I2(R)-HETE) in corneal tissues: formation of novel metabolites. Arch Biochem Biophys 1991; 290:326--335.

Biochim Biophys Acta 1987; 917:406--410. 116. Woollard PM, Murphy GM, Cunningham FM, Camp RDR, Greaves MW. Pro-inflammatory effects of 12(R)-hydroxy-S,8,1O,14-eicosatrienoic acid in human skin. (abstract) 117. Conners MS, Godfrey H, Chauhan K, Falck JR, Laniado-Schwartzman M. Enhancement of delayed-type hypersensitivity inflammatory reactions by 12(R)-hydroxy-S,8,14-eicosatrienoic acid. J Invest Dennatol 1994; 104:1-5. 118. Capdevila J, Gil L, Orellana M, Marnett LJ, Mason JI, Yadagiri P, Falck JR.

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Advances in Ocular Toxicology by Keith Green (auth.), Keith Green, Henry F. Edelhauser, Robert B. Hackett, David S. Hull, David E. Potter, Ramesh C. Tripathi (eds.)

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